Heart disease, pneumonia, asthma account for 42% of total deaths in India in 2020

Heart disease, pneumonia, asthma account for 42% of total deaths in India in 2020; covid 9 percent

Heart disease, pneumonia, asthma account for 42% of total deaths in India in 2020

While diseases of the circulatory system claimed 32.1% of lives, respiratory diseases accounted for 10% of deaths.

Of the total 18,11,688 deaths recorded in the country in 2020, heart disease, pneumonia and asthma together accounted for the highest number of deaths – over 42 per cent.

However, the total number of deaths in the country stood at 81,15,882.

According to the 2020 Medical Evidence of Cause of Death report prepared by the Registrar General and Census Commissioner of India, COVID-19, which affected the country in a single year, claimed nearly nine per cent of lives – 1, 60,618 people. ,

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While diseases of the circulatory system claimed 32.1% of lives, respiratory diseases accounted for 10% of deaths.

Those who died from pulmonary circulatory and other types of heart defects and coronary heart disease were classified as those who died from "diseases of the circulatory system."

Deaths from pneumonia, asthma, and related illnesses were referred to as deaths from "diseases of the respiratory system".

The third major group, accounting for 8.9% of total medically confirmed deaths, was classified as "special purpose code: COVID-19".

Some infectious and parasitic diseases, which rank fourth among the causes of death, are mainly represented by septicemia and tuberculosis. In 2020, they claimed 7.1% of lives in India.

The fifth leading cause, endocrine, nutritional and metabolic diseases, accounts for 5.8% of all clinically confirmed deaths. Diabetes and diabetes mellitus were the main causes of this category.

Injury, poisoning and some other result of external causes (fractures, poisoning with medicinal and biological substances) were the sixth leading cause of death in the country and accounted for 5.6% of total deaths.

Neoplasms (cancer) were the seventh leading cause, accounting for 4.7 percent of total clinically confirmed deaths.

Men and women accounted for 64 per cent and 36 per cent, respectively, of all medically confirmed deaths.

The highest number of deaths (5,17,678 or 28.6 percent of the total medically confirmed deaths) was recorded in the age group of 70 years and older.

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Diseases of the circulatory system (heart defects) ranked first among the causes of death in the age group of 45 years and above.

A total of 5.7 percent of all clinically confirmed deaths were in infants (under 1 year of age).

About 71.7% of all infant deaths are attributed to some condition occurring during the perinatal period.

In the 15-24 age group, diseases of the circulatory system accounted for 18% of deaths – the highest, followed by injury, poisoning and some other consequence of external causes, which accounted for 15.7% of deaths, indicating that the age group is particularly Vulnerable to "injuries and poisoning-related deaths".

CONCLUSION :-

Heart disease, pneumonia, asthma account for 42% of total deaths in India in 2020; covid 9 percent While diseases of the circulatory system claimed 32.1% of lives, respiratory diseases accounted for 10% of deaths. Of the total 18,11,688 deaths recorded in the country in 2020, heart disease, pneumonia and asthma together accounted for the highest number of deaths – over 42 per cent. In the 15-24 age group, diseases of the circulatory system accounted for 18% of deaths – the highest, followed by injury, poisoning and some other consequence of external causes, which accounted for 15.7% of deaths, indicating that the age group is particularly Vulnerable to injuries and poisoning-related deaths.

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SOURCE :- TRIBUNE

Why liver injury after first Remdesivir dose at PGI?

Newborn shows liver injury after first Remdesivir dose at PGI

Newborn shows liver injury after first Remdesivir dose at PGI

PGI doctors caution against its use in less severe patients

BGA researchers reported a unique case of a 14-day-old Covid-19-positive infant who exhibited liver damage after being injected with Remdesivir, a commonly used drug.in Covid-19 patients in the second wave. The research paper focused on the use of Remdesivir in young patients.

Doctors at the Center for Advanced Paediatrics, PGI, highlighted the newborn's case in an article titled “Remdesivir induced liver injury in a newborn with Covid,” published in the Indian Journal of Pediatrics.

According to the report, a newborn with Covid-19 who was diagnosed with hypoxemia (low oxygen levels) requiring intubation was admitted to the PGI. During the administration of remdesivir, the child developed transaminitis (liver infection) to stop taking the drug, and, the liver enzymes improved within two weeks.

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This 14-day-old infant developed malnutrition, lethargy, and shortness of breath on the 13th day of life. A child diagnosed with congestive heart failure requires continuous cardiopulmonary resuscitation (CPAP). A chest X-ray showed viral pneumonia and the child was positively diagnosed with Covid. The child worsened the complication and was admitted on day 5 of hospitalization.

Due to the severity of Covid pneumonia, the child was treated with Remdesivir. After starting Remdesivir, the child developed liver damage after the first injection.

Researchers say that drug-induced liver damage is different from Covid-19 liver disease and Remdesivir was discontinued after the first dose.

The researchers said that the baby's liver enzymes were gradually normalized on the 15th day of the hospital stay and that the baby was discharged on the 18th day of breastfeeding.

Because liver failure and recovery are associated with temporal association with the initiation and discontinuation of Remdesivir therapy, respectively, it was considered highly unlikely that drug-induced liver damage could occur there a lot, say the doctors.

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Remdesivir has demonstrated shorter hospital stays and modest gains in relative survival and severe Covid infection in adult patients. Remdesivir may increase transaminases and was avoided in patients with pre-existing liver failure. Remdesivir should be used with caution and limited to severe Covid infections, "the paper reads.

Remdesivir has been shown to reduce hospital stay and moderate survival benefit for moderate to severe Covid infections in adult patients. Remdesivir may increase transaminases and should not be used in patients with pre-existing liver failure. Remdesivir should be used with caution and limited to cases of severe Covid infection, "the paper said.

CONCLUSION :-

Newborn shows liver injury after first Remdesivir dose at PGI PGI doctors caution against its use in less severe patients During the administration of remdesivir, the child developed transaminitis (liver infection) to stop taking the drug, and, the liver enzymes improved within two weeks. Researchers say that drug-induced liver damage is different from Covid-19 liver disease and Remdesivir was discontinued after the first dose.

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SOURCE :- TRIBUNE