Why liver injury after first Remdesivir dose at PGI?

Newborn shows liver injury after first Remdesivir dose at PGI

Newborn shows liver injury after first Remdesivir dose at PGI

PGI doctors caution against its use in less severe patients

BGA researchers reported a unique case of a 14-day-old Covid-19-positive infant who exhibited liver damage after being injected with Remdesivir, a commonly used drug.in Covid-19 patients in the second wave. The research paper focused on the use of Remdesivir in young patients.

Doctors at the Center for Advanced Paediatrics, PGI, highlighted the newborn's case in an article titled “Remdesivir induced liver injury in a newborn with Covid,” published in the Indian Journal of Pediatrics.

According to the report, a newborn with Covid-19 who was diagnosed with hypoxemia (low oxygen levels) requiring intubation was admitted to the PGI. During the administration of remdesivir, the child developed transaminitis (liver infection) to stop taking the drug, and, the liver enzymes improved within two weeks.

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This 14-day-old infant developed malnutrition, lethargy, and shortness of breath on the 13th day of life. A child diagnosed with congestive heart failure requires continuous cardiopulmonary resuscitation (CPAP). A chest X-ray showed viral pneumonia and the child was positively diagnosed with Covid. The child worsened the complication and was admitted on day 5 of hospitalization.

Due to the severity of Covid pneumonia, the child was treated with Remdesivir. After starting Remdesivir, the child developed liver damage after the first injection.

Researchers say that drug-induced liver damage is different from Covid-19 liver disease and Remdesivir was discontinued after the first dose.

The researchers said that the baby's liver enzymes were gradually normalized on the 15th day of the hospital stay and that the baby was discharged on the 18th day of breastfeeding.

Because liver failure and recovery are associated with temporal association with the initiation and discontinuation of Remdesivir therapy, respectively, it was considered highly unlikely that drug-induced liver damage could occur there a lot, say the doctors.

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Remdesivir has demonstrated shorter hospital stays and modest gains in relative survival and severe Covid infection in adult patients. Remdesivir may increase transaminases and was avoided in patients with pre-existing liver failure. Remdesivir should be used with caution and limited to severe Covid infections, "the paper reads.

Remdesivir has been shown to reduce hospital stay and moderate survival benefit for moderate to severe Covid infections in adult patients. Remdesivir may increase transaminases and should not be used in patients with pre-existing liver failure. Remdesivir should be used with caution and limited to cases of severe Covid infection, "the paper said.

CONCLUSION :-

Newborn shows liver injury after first Remdesivir dose at PGI PGI doctors caution against its use in less severe patients During the administration of remdesivir, the child developed transaminitis (liver infection) to stop taking the drug, and, the liver enzymes improved within two weeks. Researchers say that drug-induced liver damage is different from Covid-19 liver disease and Remdesivir was discontinued after the first dose.

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SOURCE :- TRIBUNE

These 5 things affect health

These 5 things affect health, don't forget to eat before going to bed

A healthy body is everyone's choice. Over time, everyone begins to realize their health. A good diet and adequate sleep are also very important for good health. If a person does not get enough sleep, then this directly affects his health. The human body begins to be surrounded by disease. There are many things to avoid before bed. So let's find out about them...

Don't eat chocolate and pain killer

Chocolate and painkillers should never be taken at night before going to bed. Chocolate contains a large amount of caffeine. Caffeine also affects your sleep. Contains elements like Vitamin E, Antioxidants. Drinking alcohol at night can cause insomnia.

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don't eat tomatoes

Eating tomatoes at night is considered very harmful to health. Acid is found in very large amounts in it, due to which you may have problems with acidity. Tomatoes also contain carotenoids that affect your immune system.

don't eat onions

Onions should not be eaten at night. It affects your feast. Consumption of gas, builds up your stomach, which affects your sleep. This increases the amount of fat in the body. Although most doctors recommend eating onions at night. If you want to take it, be sure to consult a doctor.

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do not drink fruit juice

You should also not eat fruit at night. The acid is also found in very large quantities in it. This can cause an acidic reaction in your body. Due to the fact that your sleep can be completely affected.

do not drink alcohol

Never drink alcohol before bed. Not only in alcohol, alcohol is found in many other things. Your sleep may be affected by alcohol.

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Adolescents at risk of PCOS

Adolescents at risk of PCOS: 1 in 5 women in the country is in her grip, the main reason being obesity; Learn how to protect

Polycystic ovary syndrome (PCOS) is becoming a common disease among Indian women. According to statistics, 1 in 5 young women in the country is in her grip. Doctors believe that due to poor eating habits, the habit of sitting and ignoring the warning symptoms of the disease, the risk of PCOS increases much more.

PCOS risk in teenage girls

In a conversation with OnlyMyHealth, Dr. Raksha Madhu said that nowadays the symptoms of PCOS are observed in girls between 13 and 19 years old. This is due to excessive weight gain at this age. Let us tell you that according to a study by AIIMS, in 60% of cases of PCOS, the patient is obese.

At the same time, a study in the UK says - the mothers of 24% of women suffering from PCOS and the sisters of 32% of women also have this disease. This means that PCOS can also be a genetic syndrome.

According to Dr. Madhu, girls who live in cities are more prone to PCOS than in villages. Reasons for this include eating in restaurants and cafes, soft drinks and packaged foods, incomplete sleep, emotional stress, and negligible exercise.

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Beware of these symptoms of PCOS

severe acne

excessive growth of body hair

depression

heart disease

infertility

Diabetes

Hypertension

cancer in women

Experts believe that girls who menstruate early have a higher risk of having PCOS at some point in their lives.

Causes of PCOS in teenage girls

The biggest cause of PCOS is the deterioration of the balance of hormones. In some girls, there is an excessive production of male hormones, due to which some chemicals in the body go up and down. Obesity is the second main cause of PCOS. Being a victim of obesity in adolescence can become the root of many problems.

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How to protect against PCOS?

There is currently no permanent cure for PCOS. Its symptoms can be controlled by making changes in diet, exercising and with the help of some medicines. You can bring positive change in your life by following these tips.

Exercise daily with a 30-minute walk.

Pay attention to your weight. Avoid obesity.

Eliminate fast food from the diet and include fiber-rich food, fruits, fresh green vegetables.

Don't ignore any unusual symptoms. Contact the doctor immediately so that future complications can be avoided.

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Spinal cord problems worsen mental health, increasing the risk of anxiety and depression

 American Research Background: Spinal cord problems worsen mental health, increasing the risk of anxiety and depression

Besides stress, there are many reasons why your mood is low. University of Michigan scientists recently reported in research that 80% of people with spinal problems also have mental health problems.

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Such research

In the study, scientists examined data from two types of adults. Previously those with spinal cord injuries or problems. Their number is over 9,000. Some do not have such problems. Its number is more than 10 lakhs.

Scientists have found that people with spinal problems, from anxiety disorders to sleep disorders and and brain. Although spinal cord injury does not lead to complications such as anxiety and depression, the condition is more likely to occur in such individuals than in healthy individuals.

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Chronic pain also causes mental illness

Research says that chronic spinal pain, ie. and causes chronic pain, mental illness in humans. In many people, mental health problems are not seen because of a spinal cord injury but because of chronic pain.

What is the solution to this problem?

Scientists say doctors should also pay attention to the mental health of patients with spinal problems. If patients exhibit symptoms of mental health problems, they should be encouraged to seek treatment for the condition.

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Source: Danik Jagran

The Most Underrated Chest Pain Is Not Just a Symptom of a Heart Attack Products You Need to Know

 Chest pain is not just a symptom of a heart attack: the symptoms are different in women than in men; Often doctors do not understand

Although heart disease is the leading cause of death for men and women in India, including the United States, research suggests that women are more likely than men to ignore heart attack warning signs. Women are also reluctant to seek help because they have milder symptoms than men. So when they arrive at the hospital, doctors underestimate their symptoms or delay treatment.

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1. The symptoms of heart disease in women are somewhat different

In fact, a common symptom of heart disease in men / women is chest / chest pain or discomfort. However, many women show symptoms that are difficult to associate with heart disease. For example: difficulty breathing, feeling sick, fatigue, nausea and back pain.

The American Heart Association reports that women with chest pain have a more serious heart attack because it takes longer for both the patient and the doctor to diagnose the problem. Doctors said it was their brainwashing.

Dr. Alexandra Lansky, a cardiologist at Yale-New Haven Hospital, said: All have been referred to the dentist. The dentist removed his two molasses. However, the pain did not subside, so he came with me. Research has shown that pain is related to the heart. The woman underwent bypass surgery, after which the aching pain subsided.

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2. A campaign is underway to make women aware

A campaign is underway in the United States to make women aware of heart disease. Sweating, dizziness, or abnormal fatigue may be symptoms of heart disease. Research published in the Journal of Therapeutics and Clinical Risk Management found that 62% of women did not experience chest pain compared to 36% of men. Many women report difficulty breathing with gastrointestinal symptoms such as nausea and dyspepsia. Most people experience chest tightness or tension instead of chest pain.

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3. High blood pressure and obesity increase the risk in women aged 35-54 years

Cardiologist Dr Jacqueline Tamis-Holland said: 'People think that chest pain is the biggest symptom of a heart attack, just like in the movie, but it is not. Women are less at risk of heart disease than men. However, young women are also victims. High blood pressure and obesity increase the risk of heart attack in women between the ages of 35 and 54.

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What To Feed And Avoid For Proper Nutrition In Children?

It is very difficult to explain the importance of nutrition to children, but you can explain it through colors.

To maintain the good health of children, it is necessary that they eat 7 colored things every day, and in this way, you can explain the importance of nutrition to them through colors. 

How Less Sleep Effect Brain Function

Tell the children about the importance of which color for our body from the beginning.

1. Fiber is essential in food

It is important to have plenty of fiber in the diet of children. This keeps the health good. Give children fresh fruits, green vegetables, dry fruits, sprouted grains, milk, and other dairy products to eat.

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2. Avoid fast food

Kids love fast food. Junk foods cause great harm to health. When children insist on eating fast food, then make the burgers or noodles at home. There is a lot of filth along with adulteration in the things of the market.

Healthy Eating for Kids

3. Set meal times

Many children have a habit of eating something or the other all the time. They do not feel hungry by eating all the time. Therefore, if the child is a little older, then fix the time of his breakfast, lunch, dinner and make a habit of eating nutritious food. 

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Give them one fruit to eat at a time. Give milk and eggs daily. These things are necessary for physical and mental development.

4. Serve right

Never serve food to children in a hurry. Take special care of their plating. Even though it may take you two extra minutes to decorate it, but definitely spend time on it.

5. Don't give some things

Good and healthy eating habits should be inculcated in children from the very beginning. Do not give them to eat more sugar, salt, fried foods, and things made from flour. Often parents give biscuits, chips, cakes, and snacks to their children so that the child should eat something.

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But don't give these things at all. Because children do not get any benefit from these things and neither do they get health.

Exipure

Exipure

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Less Water Intake Can Cause 6 Damages To Your Health

If you drink less water then these 6 big damages will happen to your health

80% of the human body is comprised of water. Every organ, cell, and tissue in our body uses water to function properly, so it is important to drink enough water daily. Medical experts say that our body is mostly made up of water, so 6 to 8 glasses of water ie at least 1.2 liters of water should be smashed day by day 

If you are more active, drink more water. If you do not remember to drink enough water and because of this, you will in general drink less water, fill a bottle with you at all times. Apart from this, cucumber, watermelon, berries, lemon are also good sources of water.

What happens if you don't drink enough water?

No matter how busy you are throughout the day, intake water as much as you can per day. Lack of water in the body can lead to many problems. So let's find out what happens if you do not drink enough water?

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1. Having frequent headaches

When there is a shortage of water in your body, its first effect is seen in the form of a headache. You will have a steady migraine. But the good news is that if the headache is caused due to lack of water, it will get better after drinking a big glass of water.

2. sluggish gut

The colon has water receptors, and they draw water from the body to soften the stool. If you don't consume the required amount of water, hard stools and constipation can be common side effects, alongside stomach torment and squeezing.

3. Lifeless Skin

The lack of water in the body can be clearly seen on your face.  skin begins looking dry, lifeless, tired, and sick.

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4. Lethargy

If you do not drink enough water throughout the day, it affects your energy. You might feel lazy and befuddled. So the next time you look for coffee or tea when you're thirsty, remember that drinking water is more important.

5. Weight Gain

Sometimes people mistake thirst for hunger, furthermore, instead of drinking they eat more. Whereas they only need water. Next time you feel hungry even after eating food, have a go at drinking a couple of glasses of water, your craving will vanish. For this it is not necessary that you drink only plain water, you can likewise drink lemonade, fresh fruit juice.

6. Dry mouth

If you don't drink enough water, you may also suffer from dry mucus membranes (lack of saliva). Due to which there can be difficulty in speaking, swallowing, and even breathing. The good thing is that all these problems can be solved with a glass or two of water.

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CONCLUSION:

Medical experts say that our body is mostly made up of water, so 6 to 8 glasses of water ie at least 1. 2 liters of water should be smashed day by day If you are more active, drink more water. If you do not remember to drink enough water and because of this, you will in general drink less water, fill a bottle with you at all times. What happens if you do not drink enough water? But the good news is that if the headache is caused due to lack of water, it will get better after drinking a big glass of water.2.sluggish gut The colon has water receptors, and they draw water from the body to soften the stool. If you do not consume the required amount of water, hard stools and constipation can be common side effects, alongside stomach torment and squeezing.3. Lethargy If you do not drink enough water throughout the day, it affects your energy. The good thing is that all these problems can be solved with a glass or two of water. 2 liters of water should be smashed day by day If you do not remember to drink enough water and because of this, you will, in general, drink less water, fill a bottle with you at all times. But the good news is that if the headache is caused due to lack of water, it will get better after drinking a big glass of water.

2 liters of water should be smashed day by day If you are more active, drink more water. But the good news is that if the headache is caused due to lack of water, it will get better after drinking a big glass of water. If you do not remember to drink enough water and because of this, you will in general drink less water, fill a bottle with you at all times. Lethargy If you do not drink enough water throughout the day, it affects your energy. What happens if you do not drink enough water?Medical Medical experts say that our body is mostly made up of water, so 6 to 8 glasses of water ie at least 1.

Medical experts say that our body is mostly made up of water, so 6 to 8 glasses of water ie at least 1.2 liters of water should be smashed day by day If you do not remember to drink enough water and because of this, you will, in general, drink less water, fill a bottle with you at all times. But the good news is that if the headache is caused due to lack of water, it will get better after drinking a big glass of water.

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To Control Cholesterol Levels, Drink Tea Of ​​Locat Leaves Daily

There are two kinds of cholesterol - great and terrible cholesterol. To control cholesterol levels, drink tea of ​​local leaves daily

It is discharged in the liver. It is a type of fat, which is found in every one of the cells of the body. Cholesterol helps in the formation of many essential elements in the body, counting chemicals and nutrients. Good cholesterol strengthens the digestive system. 

At the same time, blood circulation is affected by bad cholesterol. Because of this, the risk of heart attack and high blood pressure increases. Doctors always recommend taking a balanced diet to control cholesterol. If you are also troubled by rising cholesterol, then drink herbal tea daily and consume sunflower seeds. It has been revealed in many types of research that drinking herbal tea keeps cholesterol under control.

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let's know more about it

Eat sunflower seeds:

Antioxidants, minerals, vitamins, and nutrients are found in sunflower seeds, which also prove to be beneficial for good cholesterol. This expands great cholesterol. Also, terrible cholesterol is diminished. For this, to lower the rising cholesterol level, take a small bunch of sunflower seeds day by day. If you want, you can consume sunflower seeds by adding them to the salad. Apart from this, you can likewise eat broiled sunflower seeds.

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Drink loquat leaf tea:

Loquat fruit is used as medicine in Ayurveda. Its taste is unpleasant and sweet. It has many medicinal properties including rich in antioxidants and vitamin C, which are effective in controlling rising cholesterol. According to research, anti-atherosclerotic properties are found in the leaves of loquat. Its consumption helps in controlling the rising cholesterol. For this, make tea from the leaves of Lokat and drink it daily.

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To look Attractive, Start Doing These 5 Asanas Today.

Through yoga, the face can be kept beautiful, soft, and young for a long time, start doing these 5 asanas today.

But most of us trust and use expensive products, which give a no doubt glow but there is no guarantee that its effect will last for a long time. So if you want to beautify the face naturally and stay young, then.

Include these yoga asanas in your routine:

1. child pose

Balasan is a very good posture to increase the glow and beauty of the face. While doing this asana, there is blood circulation towards the face, due to which the problem of wrinkles is also removed along with the glow.

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2. Downward dog pose

Even in the downward-facing dog posture, the blood flow is towards the face and head. Because of which issues like pimples, freckles, wrinkles stay away. The glow of the face increases with the practice of this asana daily. Apart from this, this posture is also very beneficial for hair as well as obesity, back pain.

3. Bhujangasana (Cobra Pose)

Bhujangasana is a very beneficial anti-aging yoga posture that keeps both the face and the body young for a long time. Along with this, it is also good for reducing stomach, reducing weight, providing relief in back pain and lungs.

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4. Chakrasana (Wheel Pose)

It would not be wrong to call Chakrasana an anti-aging posture, because while doing it, the shape of the body that is formed in it, the flow of blood towards the face increases, due to which the glow increases, as well as the face, looks attractive. It is a great exercise to get rid of wrinkles. 

5. Shoulder stand pose

While doing Sarvangasana, the feet are up in the air and the neck is on the ground, the weight of the whole body is on the shoulders. Due to which the blood flow is faster towards the face and head. Daily practice of this asana brings redness on the face, due to which the hair also becomes strong. 

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CONCLUSION:

While doing this asana, there is blood circulation towards the face, due to which the problem of wrinkles is also removed along with the glow. Bhujangasana is a very beneficial anti-aging yoga posture that keeps both the face and the body young for a long time.

It would not be wrong to call Chakrasana an anti-aging posture, because while doing it, the shape of the body that is formed in it, the flow of blood towards the face increases, due to which the glow increases, as well as the face, looks attractive.

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These Are The Symptoms Of 'Pre-Diabetes In Individuals!

Pre-diabetes means the condition in which you do not have diabetes, These are the symptoms!

But you are standing on the threshold of this disease. A slight deficiency in diet, exercise, and lifestyle can give you diabetes for life. Pre-diabetes is considered the pre-diabetes stage. This means that the body starts signaling to you that if you do not take care of your health, then type 2 diabetes is not far away. 

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Many peoples didn't know, which involves concern. Know more

Symptoms of Pre-Diabetes

Diabetes is a disease for which there is no cure, but it can be kept under control with the help of medicines and lifestyle changes. Your risk of becoming pre-diabetic is when you begin to:

- Excessive thirst Feeling thirsty even after drinking enough water.

- frequent urination.

- Being very tired without working.

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-The onset of the problem of high blood pressure.

Sudden weight gain. Fats are visible,  around the midsection. Waist sizes 35 inches for women and 40 inches for men can be dangerous.

Increased appetite can also be a sign of pre-diabetic.

Due to PCOD in women, periods become irregular, which can also be a symptom of pre-diabetes.

If your eyes suddenly become weak, then it can also be a sign of pre-diabetes. High cholesterol not only harms heart health, but it can also be a cause of pre-diabetes.

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If you see any of these symptoms, be sure to get your blood test done. If your blood sugar level is high, then consult a doctor immediately.

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